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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1015 | NFAT Inhibitor | VIVIT peptide | Others |
NFAT Inhibitor (VIVIT peptide) is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation of NFAT. | |||
T50103 | NFAT Inhibitor-2 | Others | |
NFAT Inhibitor-2 is a compound used as a molecular building block. | |||
TP1978L | NFAT inhibitor, Cell Permeable aceate | Others | |
NFAT inhibitor, Cell Permeable aceate is a cell-permeable nuclear factor of activated T cells (NFAT) inhibitor. It can be used for the research of podocyte and diabetic nephropathy. | |||
TP1015L | NFAT Inhibitor acetate | VIVIT peptide acetate,NFAT Inhibitor acetate(249537-73-3 free base) | |
NFAT Inhibitor acetate (VIVIT peptide acetate) is a cell-permeable and selective NFAT peptide inhibitor of calmodulin phosphatase-mediated NFAT dephosphorylation. | |||
T27612 | INI-43 | INI 43,INI43 | Others |
INI-43, an inhibitor of Nuclear Import-43, shows a significant cytotoxic effect on various cervical and oesophageal cancer cell lines by targeting Kpnβ1 and interferes with the nuclear localization of Kpnβ1 and known Kpn... | |||
TP1978 | 11R-VIVIT | NFAT inhibitor, Cell Permeable | |
NFAT inhibitor. Inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). Also attenuates NO production and Nos2 mRNA expression in LPS-stimulated ... | |||
T21807 | INCA-6 | Triptycene-1,4-quinone | Others |
INCA-6 (Triptycene-1,4-quinone) is a cell-permeable NFAT inhibitor. INCA-6 inhibits of CN-NFAT signaling by targeting of NFAT(P) substrate to the calcineurin (CN) phosphatase site. | |||
T23186 | ProINDY | Pro-indy | DYRK |
ProINDY (Pro-indy) is a potent DYRK inhibitor that activates NFAT for the study of Down syndrome. | |||
T12218 | NFAT Transcription Factor Regulator-1 | IL Receptor | |
NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM). | |||
T35885 | KRM-III | Others | |
KRM-III is an orally active T cell antigen receptor (TCR) inhibitor with anti-inflammatory activity that potently inhibits TCR and myristate acetate/fosfomycin/ionomycin-induced NFAT nuclear factor activation and T cell ... | |||
T5339 | YZ129 | ||
YZ129, a glioblastoma inhibitor, targets the HSP90-calcineurin-NFAT pathway by directly binding to heat shock protein 90 (HSP90) and exhibits an IC 50 of 820 nM on NFAT nuclear translocation. It induces cell-cycle arrest... | |||
T69754 | BTP1 | ||
BTP1 is an inhibitor of NFAT activation and T-cell cytokine production. BTP1 potently inhibits SOCE in many cells with considerable selectivity over voltage-gated Ca2+ entry. | |||
T71295 | SOR-C13 | ||
SOR-C13 is an inhibitor of transient receptor potential cation channel vanilloid family member 6 (TRPV6, CaT1 or CATL) with potential antineoplastic activity. TRPV6 calcium channel inhibitor SOR-C13 binds to TRPV6 and pr... |